The CFTR2 project is partially supported by Grant Number 5R37DK044003 from the
National Institute of Digestive, Diabetes and Kidney Diseases of the National Institutes of Health, by funding from the US Cystic Fibrosis
Foundation, and by an unrestricted educational grant from Sequenom to the US Cystic Fibrosis Foundation.
How to use this website
WHAT YOU CAN LEARN FROM THIS WEBSITE:
This website can be used to search the CFTR2 database for information about patients in the CFTR2 database with specific CFTR mutations.
When a specific mutation is entered into the "Search Mutations Database" search engine, the following information will be provided:
Whether this mutation will cause CF when it is combined with another mutation that causes CF.
REMEMBER: In order to have CF, a patient must have 2 copies of a CFTR mutation, one that is inherited from the father and one from the mother.
They can be 2 copies of the same mutation that causes CF OR 2 different mutations that both cause CF. **If only 1 CFTR mutation is present, the patient is a CF carrier, but the person will NOT have CF.
Whether patients with this mutation need to take pancreatic enzyme supplements. (This is called “pancreatic insufficiency.”)
How well the lungs works in patients with this mutation at the time the information in the database was collected.
The average age of patients in the database with this mutation at the time the information in the database was collected.
Whether the lungs of most patients with this mutation have been infected with pseudomonas aeruginosa bacteria.
The following information describes how to use the website and explains the information that is provided on each page.
Permitted use available to clinicians, patients, and family members for clinical, research, and educational uses only. All other rights reserved.
@ Copyright 2011 US CF Foundation, Johns Hopkins University, The Hospital for Sick Children.
